5.2 AS Level

Chromosome behaviour in

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Key Concept Flip

Describe the key events occurring during prophase of mitosis.

Answer Flip

Chromatin condenses into visible chromosomes (each with two sister chromatids), the nuclear envelope breaks down, and the spindle apparatus begins to form from the centrosomes. Microtubules attach to the kinetochores of the sister chromatids.

Definition Flip

What is the role of the spindle during mitosis?

Answer Flip

The spindle, composed of microtubules, is responsible for accurately segregating the sister chromatids to opposite poles of the cell during anaphase. This ensures each daughter cell receives a complete set of chromosomes.

Key Concept Flip

Outline the events that occur during metaphase.

Answer Flip

The chromosomes line up along the metaphase plate (equator) of the cell, with each sister chromatid attached to a spindle fiber originating from opposite poles. This ensures equal distribution of genetic material.

Key Concept Flip

Describe the main events during anaphase.

Answer Flip

Sister chromatids are separated and pulled to opposite poles of the cell by the shortening of spindle fibers. Each chromatid is now considered an individual chromosome.

Key Concept Flip

What occurs during telophase of mitosis?

Answer Flip

The chromosomes arrive at the poles and begin to decondense. The nuclear envelope reforms around each set of chromosomes, and the spindle apparatus disappears. Cytokinesis usually occurs concurrently.

Key Concept Flip

What happens to the nuclear envelope during mitosis?

Answer Flip

The nuclear envelope breaks down during prophase, allowing the spindle fibers to access the chromosomes. It reforms during telophase around the separated chromosomes, creating two distinct nuclei.

Key Concept Flip

Explain the process of cytokinesis in animal cells.

Answer Flip

In animal cells, cytokinesis involves the formation of a cleavage furrow, a contractile ring of actin and myosin filaments that pinches the cell membrane inward, eventually dividing the cytoplasm into two daughter cells.

Key Concept Flip

How does cytokinesis differ in plant cells compared to animal cells?

Answer Flip

Plant cells form a cell plate, a new cell wall, between the two daughter nuclei. Vesicles containing cell wall material fuse at the midline, expanding outward until the new cell wall completely separates the two cells.

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5.1 Replication and division of 6.1 Structure of nucleic acids