15.1 A2 Level

Control and coordination in mammals

Cambridge A-Level Biology (9700)  · Unit 15: Control and coordination  · 10 flashcards

Control and coordination in mammals is topic 15.1 in the Cambridge A-Level Biology (9700) syllabus , positioned in Unit 15 — Control and coordination , alongside Control and coordination in plants.  In one line: Sensory neurones have a cell body located off to the side of the axon, a long dendron extending from the sensory receptor to the cell body, and a short axon carrying impulses to the central nervous system. Function is to transmit sensory information from receptors to CNS.

Marked as A2 Level: examined at A Level in Paper 4 (A Level Structured Questions) and Paper 5 (Planning, Analysis and Evaluation). It is not tested on the AS-only papers (Papers 1, 2 and 3).

The deck below contains 10 flashcards — 1 definition and 9 key concepts — covering the precise wording mark schemes reward.  Use the definition card to lock down command-word answers (define, state), then move on to the concept and calculation cards to handle explain, describe, calculate and compare questions.

Key definition

Describe the structure of a sensory neurone, including the location and function of its key components

Sensory neurones have a cell body located off to the side of the axon, a long dendron extending from the sensory receptor to the cell body, and a short axon carrying impulses to the central nervous system. Function is to transmit sensory information from receptors to CNS.

What the Cambridge 9700 syllabus says

2025-2027 syllabus, in our words · A2 Level

What the syllabus expects you to be able to do in this topic, in plain English. For the exact wording, see the official syllabus (PDF).

  1. Describe the endocrine system's features, using the hormones insulin, glucagon and ADH as reference points (see 14.1.8 to 14.1.10).
  2. Compare the nervous system's features with those of the endocrine system.
  3. Describe how sensory and motor neurones are structured and what they do, and state that intermediate neurones link sensory to motor neurones.
  4. Outline how sensory receptor cells detect stimuli and trigger impulses to be transmitted along sensory neurones.
  5. Describe, with a chemoreceptor cell from a taste bud in humans as the example, the series of events that leads to a sensory neurone producing an action potential.
  6. Describe and explain how a neurone's membrane potential changes, including: maintenance of the resting potential; the events of an action potential; restoration of the resting potential during the refractory period.
  7. Describe and explain how saltatory conduction lets impulses travel rapidly along myelinated neurones.
  8. Explain why the refractory period matters in setting how often impulses can be sent (their frequency).
  9. Describe how a cholinergic synapse is structured and explain how it works, including what calcium ions do.
  10. Describe how neuromuscular junctions, the sarcoplasmic reticulum and the T-tubule system each help to stimulate striated muscle to contract.
  11. Use diagrams and electron micrographs to describe the fine structure (ultrastructure) of striated muscle, focusing on how a sarcomere is built.
  12. Explain how muscles contract according to the sliding filament model, including the roles of tropomyosin, troponin, ATP and calcium ions.

Cambridge syllabus keywords to use in your answers

These are the official Cambridge 9700 terms tagged to this section. Mark schemes credit responses that use the exact term — weave them into your answers verbatim rather than paraphrasing.

endocrine system sensory neurone motor neurone action potential resting potential saltatory conduction refractory period cholinergic synapse striated muscle sarcomere

Tips to avoid common mistakes in Control and coordination in mammals

Key Concept Flip

Compare and contrast the nervous and endocrine systems in terms of speed, duration, and signal transmission.

Answer Flip

The nervous system uses electrical impulses for rapid, short-duration responses, transmitted via neurons. The endocrine system uses hormones for slower, longer-duration responses, transmitted via the bloodstream.

Example: Nervous system - immediate response to danger; Endocrine system - long-term growth.
Definition Flip

Describe the structure of a sensory neurone, including the location and function of its key components.

Answer Flip

Sensory neurones have a cell body located off to the side of the axon, a long dendron extending from the sensory receptor to the cell body, and a short axon carrying impulses to the central nervous system. Function is to transmit sensory information from receptors to CNS.

Key Concept Flip

Outline the role of sensory receptor cells in initiating a nerve impulse.

Answer Flip

Sensory receptor cells detect specific stimuli (

Example: light, pressure, chemicals). When stimulated, they generate a receptor potential that, if strong enough, triggers an action potential in the connected sensory neurone, initiating an impulse.
Key Concept Flip

Describe the key steps involved in generating an action potential in a sensory neurone, using a chemoreceptor in a taste bud as an example.

Answer Flip

Na⁺ from salty food diffuses into the chemoreceptor cell through Na⁺ channels, depolarising it (receptor potential). This opens voltage-gated Ca²⁺ channels, Ca²⁺ enters, and vesicles release neurotransmitter onto the sensory neurone. The neurotransmitter depolarises the sensory neurone, and if threshold is reached, an action potential is generated in it.

Key Concept Flip

Explain how the resting potential of a neurone is maintained.

Answer Flip

The resting potential is maintained by the sodium-potassium pump, which actively transports 3 Na+ ions out of the cell and 2 K+ ions into the cell. Additionally, the membrane is more permeable to K+ than Na+, resulting in a negative charge inside the cell.

Key Concept Flip

Explain the role of voltage-gated ion channels in the generation of an action potential.

Answer Flip

Voltage-gated Na+ channels open when the membrane potential reaches threshold, allowing Na+ to rush into the cell and cause rapid depolarization. Voltage-gated K+ channels then open, allowing K+ to flow out of the cell, causing repolarization.

Key Concept Flip

Describe saltatory conduction and explain its advantages in impulse transmission.

Answer Flip

Saltatory conduction is the 'jumping' of an action potential between Nodes of Ranvier in myelinated neurones. This increases the speed of impulse transmission significantly compared to unmyelinated neurones, as depolarization only occurs at the nodes.

Key Concept Flip

Explain the importance of the refractory period following an action potential.

Answer Flip

The refractory period ensures that action potentials travel in one direction only (down the axon). It also limits the frequency of action potentials, preventing continuous stimulation and allowing for discrete signal encoding.

Key Concept Flip

Describe the sequence of events at a cholinergic synapse that leads to the transmission of a nerve impulse across the synaptic cleft.

Answer Flip

Action potential arrives, voltage-gated Ca2+ channels open, Ca2+ influx triggers exocytosis of vesicles containing acetylcholine (ACh). ACh diffuses across the cleft, binds to receptors on the postsynaptic membrane, causing Na+ channels to open, leading to depolarization.

Key Concept Flip

Explain the role of calcium ions in muscle contraction.

Answer Flip

Calcium ions bind to troponin, causing a conformational change that moves tropomyosin away from the myosin-binding sites on actin. This allows myosin heads to bind to actin, forming cross-bridges and initiating the sliding filament mechanism.

Review the material

Read full revision notes on Control and coordination in mammals — definitions, equations, common mistakes, and exam tips.

Read Notes

More Biology flashcards

Browse every 9700 flashcard topic by syllabus area.

All Biology Flashcards
14.2 Homeostasis in plants 15.2 Control and coordination in plants

More topics in Unit 15 — Control and coordination

Control and coordination in mammals sits alongside these A-Level Biology decks in the same syllabus unit. Each uses the same spaced-repetition system, so progress in one informs the next.

Key terms covered in this Control and coordination in mammals deck

Every term below is defined in the flashcards above. Use the list as a quick recall test before your exam — if you can't define one of these in your own words, flip back to that card.

Describe the structure of a sensory neurone, including the location and function of its key components

How to study this Control and coordination in mammals deck

Start in Study Mode, attempt each card before flipping, then rate Hard, Okay or Easy. Cards you rate Hard come back within a day; cards you rate Easy push out to weeks. Your progress is saved in your browser, so come back daily for 5–10 minute reviews until every card reads Mastered.